*Should you be involved in a medical demo for either merchandise, adverse gatherings need to be reported towards your coordinating research web-site. If you cannot use the above Internet site to report an adverse party related to a copyright product, make sure you get in touch with copyright healthcare info at (800) 438-1985. FDA Medwatch
Animal information Formal reproductive and developmental toxicology experiments for meperidine have not been concluded.
If concomitant use is important, consider rising the DEMEROL Injection dosage until secure drug effects are obtained.
Opioids are sought for nonmedical use and so are subject to diversion from legit prescribed use. tactics to reduce these dangers include prescribing the drug within the smallest appropriate quantity.
observe people for indications of diminished diuresis and/or effects on hypertension and boost the dosage of your diuretic as required.
DEMEROL Injection might impair the psychological or Actual physical skills needed to execute most likely hazardous actions like driving an automobile or running equipment.
Meperidine is drastically much less helpful by the oral than because of the parenteral route, more info but the precise ratio of oral to parenteral performance is not known.
observe sufferers for indications of urinary retention or reduced gastric motility when DEMEROL Injection is used concomitantly with anticholinergic medicine.
advise people of the potential risk of everyday living-threatening respiratory melancholy, which include information that the risk is best when DEMEROL Injection or when the dosage is greater, and that it can happen even at advised dosages [see Warnings and safeguards (5.two)].
Phenytoin: The hepatic metabolism of meperidine might be Improved by phenytoin. Concomitant administration resulted in reduced half-existence and bioavailability with elevated clearance of meperidine in balanced topics; on the other hand, blood concentrations of normeperidine ended up elevated [see Drug Interactions (7)].
We foresee reposting the photographs when we are capable determine and filter out photographs that don't match the information delivered during the drug labels. NDC Codes
Observational scientific tests have shown that concomitant usage of opioid analgesics and benzodiazepines enhances the possibility of drug-similar mortality in comparison with usage of opioid analgesics by itself.
Respiratory despair would be the Main chance for aged sufferers treated with opioids, and it has transpired right after big Preliminary doses ended up administered to people who weren't opioid-tolerant or when opioids were co-administered with other brokers that depress respiration.
This medication might be employed for other functions; inquire your health and fitness care provider or pharmacist When you've got inquiries.